Literatur AVP 2/2003

Literatur zu: Ezetimib (Ezetrol®), ein neuer

Cholesterinsenker

1. Bays HE, Moore PB, Drehobl MA et al.:

Effectiveness and tolerability of ezetimibe in patients with primary

hypercholesterolemia: pooled analysis of two phase II studies. Clin Ther 2001;

23:1209–1230.

2. Sudhop T,von Bergmann K: Cholesterol

absorption inhibitors for the treatment of hypercholesterolaemia. Drugs 2002;

62: 2333–2347.

3. Gagne C, Bays HE, Weiss SR et al.: Efficacy

and safety of ezetimibe added to ongoing statin therapy for treatment of

patients with primary hypercholesterolemia. Am J Cardiol 2002; 90: 1084–1091.

4. Gagne C, Gaudet D, Bruckert E: Efficacy and

safety of ezetimibe coadministered with atorvastatin or simvastatin in patients

with homozygous familial hypercholesterolemia. Circulation 2002; 105: 2469–2475.

5. MRC/BHF Heart Protection Study of

cholesterol lowering with simvastatin in 20,536 high-risk individuals: a

randomised placebo-controlled trial. Lancet 2002; 360: 7–22.

6. Rosenson RS: Non-lipid-lowering effects of

statins on atherosclerosis. Curr Cardiol Rep 1999; 1: 225–2232.

7. Rosenson RS,.Tangney CC:

Antiatherothrombotic properties of statins: implications for cardiovascular

event reduction. JAMA 1998; 279: 1643–1650.

8. Vaughan CJ, Murphy MB, Buckley BM: Statins

do more than just lower cholesterol. Lancet 1996; 348: 1079–1082.

9. Liao JK: Beyond lipid lowering: the role of

statins in vascular protection. Int JCardiol 2002; 86: 5–18.