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 Drug Commission of the
 German Medical Association
 Herbert-Lewin-Platz 1
 D-10623 Berlin
 Phone:
 Fax:
 Contact:
+49 30 400456-500
+49 30 400456-555
info@akdae.de
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AkdÄ  >  Current drug review, flyer

"Wirkstoff aktuell" (current drug review), flyer

"Wirkstoff aktuell" is an information of the National Association of Statutory Health Insurance Physicians - in cooperation with the DCGMA - about newly introduced drugs. These evidence-based information describe the significance of new drugs regarding to a certain indication. Thereby, the general practitioner has a neutral information that helps him to make the right decision on prescription.

Latest issues:

Wirkstoff aktuell Pimecrolimus (Elidel®); Tacrolimus (Protopic®)
Wirkstoff aktuell
Pimecrolimus (Elidel®);
Tacrolimus (Protopic®)


PDF document (Acrobat Reader required)  WA 7/2007 [PDF]
  Wirkstoff aktuell Exenatide (Byetta®)
Wirkstoff aktuell
Exenatide (Byetta®)



PDF document (Acrobat Reader required)  WA 6/2007 [PDF]
  Wirkstoff aktuell Tigecyclin (Tygacil®)
Wirkstoff aktuell
Tigecyclin (Tygacil®)



PDF document (Acrobat Reader required)  WA 5/2007 [PDF]
  Wirkstoff aktuell Rotigotin (Neupro® 2, 4, 6, 8 mg/24 h)
Wirkstoff aktuell
Rotigotin (Neupro®
2, 4, 6, 8 mg/24 h)


PDF document (Acrobat Reader required)  WA 4/2007 [PDF]

All issues:

PDF-Dokument (Acrobat Reader erforderlich)  "Wirkstoff aktuell" Zoledronic acid (Aclasta® 5 mg infusion solution)  [PDF]
("Wirkstoff aktuell" 04/2008)  According to the efficiency, there is no evidence for the advantage of zoledronic acid compared to the more favorably priced oral bisphosphonates in the treatment of postmenopausal women with osteoporosis.

PDF-Dokument (Acrobat Reader erforderlich)  Pimecrolimus (Elidel®); Tacrolimus (Protopic®)  [PDF]
("Wirkstoff aktuell" 07/2007) 

PDF-Dokument (Acrobat Reader erforderlich)  Exenatide (Byetta®)  [PDF]
("Wirkstoff aktuell" 06/2007)  Insulin is the preferred substance in the treatment of patients with type 2 diabetes mellitus that could not reach normoglycaemia with the help of oral antidiabetic agents. Exenatide can be indicated in special cases. The high costs of treatment should be taken into consideration.

PDF-Dokument (Acrobat Reader erforderlich)  Tigecyclin (Tygacil®)  [PDF]
("Wirkstoff aktuell" 05/2007) 

PDF-Dokument (Acrobat Reader erforderlich)  Rotigotin (Neupro® 2, 4, 6, 8 mg/24 h)  [PDF]
("Wirkstoff aktuell" 04/2007) 

PDF-Dokument (Acrobat Reader erforderlich)  Natalizumab (Tysabri®)  [PDF]
("Wirkstoff aktuell" of 21.06.2007) 

PDF-Dokument (Acrobat Reader erforderlich)  Pantoprazol (Pantozol® 20 mg, 40 mg; Rifun® 20 mg, 40 mg)  [PDF]
("Wirkstoff aktuell" 03/2007) 

PDF-Dokument (Acrobat Reader erforderlich)  Pregabalin (Lyrica® capsules)  [PDF]
("Wirkstoff aktuell" 02/2007) 

PDF-Dokument (Acrobat Reader erforderlich)  Neuraminidase inhibitors (oseltamivir (Tamiflu®); zanamivir (Relenza))  [PDF]
("Wirkstoff aktuell" 01/2007)  According to present epidemiologic findings the neuraminidase inhibitors oseltamivir and zanamivir do not have an additional use in the treatment of seasonal influenza but increase the costs. Besides hygienic measures the influenza vaccination is important for the prevention of infections. There is no evidence for the efficiency of neuraminidase inhibitors for the prevention and treatment of avian influenza ("bird flu") in humans. This online version of "Wirkstoff aktuell" includes additional information to the printed version (insert of "Deutsches Arzteblatt" (Journal of the German Medical Association), issue 12 of 23.03.2007). In the online version has been taken into account that Relenza is approved for the prevention of influenza too.

PDF-Dokument (Acrobat Reader erforderlich)  Quetiapine (Seroquel®)  [PDF]
("Wirkstoff aktuell" 05/2006)  The low-priced typical (= conventional, classic) antipsychotics like haloperidol do not show a lower efficiency in the treatment of schizophrenic psychosis than the atypical antipsychotic group. The expensive quetiapine is not a superior drug in schizophrenia treatment.

PDF-Dokument (Acrobat Reader erforderlich)  Etanercept (Enbrel®) in patients with rheumatoid arthritis  [PDF]
("Wirkstoff aktuell" 04/2006)  In patients with refractory rheumatoid arthritis etanercept (Enbrel®) is an effective, but expensive drug of second quality. Special attention should be paid to the serious risks of the TNF-alpha blockade.

PDF-Dokument (Acrobat Reader erforderlich)  Infliximab (Remicade®) in patients with rheumatoid arthritis  [PDF]
("Wirkstoff aktuell" 03/2006)  In patients with refractory rheumatoid arthritis infliximab (Remicade®) is an effective, but expensive drug of second quality. Special attention should be paid to the serious risks of the TNF-alpha blockade.

PDF-Dokument (Acrobat Reader erforderlich)  Esomeprazole (Nexium mups 20 mg®, Nexium mups 40 mg®)  [PDF]
("Wirkstoff aktuell" 02/2006)  In comparison to other proton pump inhibitors Esomeprazole shows no clinically relevant difference in effectiveness. More competitive omeprazole generic drugs achieve the same therapeutic success.

PDF-Dokument (Acrobat Reader erforderlich)  Nicotinic acid (Niaspan® extended-release tablets)  [PDF]
("Wirkstoff aktuell" 01/2006)  Niaspan® is approved for the treatment of patients with lipid metabolism disorders, especially with high LDL cholesterol and high triglycerides as well as low HDL cholesterol. It can also be used for the treatment of patients with primary hypercholesterolemia in combination with a HMG-CoA reductase inhibitor. It is indicated as monotherapy only in patients who do not tolerate HMG-CoA reductase inhibitors. Diet and other non-pharmacological measures should be continued.

PDF-Dokument (Acrobat Reader erforderlich)  Atomoxetine (Strattera® capsules)  [PDF]
("Wirkstoff aktuell" 04/2005)  Atomoxetine is approved to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in children at the age of 6 years and older and in adolescents as part of an extensive treatment programme.

PDF-Dokument (Acrobat Reader erforderlich)  Moxifloxacine (Avalox®)  [PDF]
("Wirkstoff aktuell" 03/2005) 

PDF-Dokument (Acrobat Reader erforderlich)  Sevelamer (Renagel®)  [PDF]
("Wirkstoff aktuell" 02/2005) 

PDF-Dokument (Acrobat Reader erforderlich)  Valdecoxib (Bextra®)  [PDF]
("Wirkstoff aktuell" 09/2004) 

PDF-Dokument (Acrobat Reader erforderlich)  Levocetirizine (Xusal®)  [PDF]
("Wirkstoff aktuell" 01/2004) 

PDF-Dokument (Acrobat Reader erforderlich)  Ezetimibe (Ezetrol®)  [PDF]
("Wirkstoff aktuell" 03/2003) 

PDF-Dokument (Acrobat Reader erforderlich)  Telithromycin (Ketek®)  [PDF]
("Wirkstoff aktuell" 02/2002) 

PDF-Dokument (Acrobat Reader erforderlich)  Folic acid  [PDF]
("Wirkstoff aktuell" 01/2002) 

PDF-Dokument (Acrobat Reader erforderlich)  Peginterferons (PegIntron® and Pegasys®)  [PDF]
("Wirkstoff aktuell" 05/2001) 

PDF-Dokument (Acrobat Reader erforderlich)  Ribavirin (Rebetol®)  [PDF]
("Wirkstoff aktuell" 02/2001) 

PDF-Dokument (Acrobat Reader erforderlich)  Thiazolidinediones ("Glitazone")  [PDF]
("Wirkstoff aktuell" 01/2001) 

PDF-Dokument (Acrobat Reader erforderlich)  Azathioprine (Imurek®)  [PDF]
("Wirkstoff aktuell" 02/2000) 

PDF-Dokument (Acrobat Reader erforderlich)  Palivizumab (Synagis®)  [PDF]
("Wirkstoff aktuell" 01/2000) 

 

 

 

 

 

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